PD Dr. med. Michael Quante (group leader)
Michael Quante (CV) begun his doctoral studies in 2001 in the laboratory of Oliver Opitz at the University of Freiburg, investigating the transcriptional regulation and activity of human telomerase in a cellular model representing important known genetic alterations observed in esophageal cancer. Following this thesis work, done during medical school at Freiburg University, he started his clinical training at the Department of Medicine, University Medical Center Bonn in 2006, with a plan for a fellowship in Gastroenterology. In 2008 Michael began his postdoctoral fellowship in the laboratory of Timothy Wang at Columbia University in New York. There he focused on a translational research approach studying the pathogenesis of gastrointestinal cancers in genetically engineered mouse models with a focus on Barrett Esophagus and Adenocarcinoma of the Esophagus. Furthermore, he investigated the function and role of tissue stem cells in gut physiology and during carcinogenesis. Michael joined the Klinikum rechts der Isar, Technische Universität München, in Mai 2011, where he is continuing his investigations into the pathogenesis of esophageal cancer to therapeutic interventions and the stem cell biology of the gut.
Dr. Frederik Wein (PostDoc)
Frederik Wein studied molecular biology in Mainz and Heidelberg where he also gained his Phd degree investigating human adult stem cells and their cellular niche in the dept. of Oncology of the University Hospital. After a brief PostDoc period in Switzerland he joined the group of Prof. Ralf Küppers in Essen to address the pathogenesis of Hodgkin lymphoma, the cancer stem cells characteristic, and tumor evasion strategies in a chronic inflammatory tumor microenvironment. In the summer of 2017 Frederik joined Dr. Michael Quante’s group to investigate the complex interplay of cancer stem cells and inflammation with genetically engineered mouse models that mimic human Barrett Esophagus and Adenocarcinoma of the Esophagus.
Theresa Baumeister (PhD Student)
Theresa Baumeister studied Biology at the TUM in Freising, Weihenstephan. She finished her Bachelor´s thesis in 2014 at the Helmholtz-Center Munich (ISF, AG Götz), working on the role of the aryl signaling pathway in neurogenesis. She finished her master´s studies in 2017. She did her Master´s thesis at the Helmholtz-Center Munich (IDG, AG Floss), where she performed ChIP sequencing of REST mutant mice to research the role of the gene REST in neuronal degeneration and Alzheimer´s disease in collaboration with the Max Planck institute of psychiatry (AG Deussing). Her strong interest in medical research led her to start her PhD at the Klinikum rechts der Isar, where she joined the Quante Lab. There she studies the role of bile acids in the development of Barrett´s esophagus.
Akanksha Anand (PhD Student)
Akanksha Anand studied bachelor of engineering in biotechnology from Thapar University in India. After completing her bachelor studies, she worked in a cancer research institute in India where she focussed on estimation of ploidy levels in liquid based cytology samples using Flow Cytometry. She was also involved in a project based on Inflammatory Demyelinating disorders of central nervous system. In 2014, she moved to United States to do her masters in biotechnology from New York University. She did her master’s thesis in Timothy Wang’s lab at Columbia University where she studied the role of IL-1beta in pancreatic cancer development and pre-clinical evaluation of candidate drugs in treating pancreatic cancer. She has now started her PhD at Klinikum rechts der Isar where she will study the signalling pathways involved in the advancement of barrett’s esophagus to esophageal adenocarcinoma.
Vincenz Sahm (Cand. Med.)
After finishing his pre-clinical studies at LMU München, Vincenz Sahm decided to continue his medical studies at the university hospital Klinikum Rechts der Isar of the TU München. His interest in experimental oncology research led him to join the Quante Lab in December 2014. He is currently investigating the relevance of telomere-length for tumor development and maintenance, using experimental methods such as cell-cultural growth-analysis and FISH-staining of paraffin slides from murine and human tissue.
Nicole Radani (Cand. Med.)
Nicole Radani studies medicine at the Ludwig-Maximilians-University in Munich. During her time in college and from the experience she gained at internships, she found out her passion for oncology research. She joined Quante Lab on February 2017, where she studies the role of bile acids and microbiome in the development of Barrett’s esophagus and Adenocarcinoma of the esophagogastric junction analysing human tissue and human microbiome. The methods she is currently using in our lab are Immunohistochemistry and PCR amplification from paraffin-embedded tissue.
Jonas Ingermann (PhD Student)
Jonas Ingermann studied biology at the Technical University Munich in Weihenstephan and finished his bachelor studies in 2011. He then changed to the Ludwigs-Maximilians-University Munich where he focused on human biology and genetics and finished his masters studies in 2013. He wrote his master’s thesis at the chair of Human Biology & BioImaging of Prof. Dr. Heinrich Leonhardt where he worked on a high content analysis system of protein-protein interactions using a fluorescent three hybrid assay. He has now started his PhD studies at the Klinikum Rechts der Isar to analyze the influence of the microbiome and nutrition on the development of esophageal cancer.
Julia Strangmann (VMTA)
Julia Strangmann graduated from the University of Veterinary Medicine Hannover as a Veterinary Medical Laboratory Technician and has over 15 years of professional experience in research and diagnostics.
Her former work at the LMU Munich was focused on immunology, neuroproteomics, experimental neuropathology and leading the histology laboratory for patient care and dissection.
In Michael Quante`s team Julia is responsible for immunohistochemical and immunofluorescent studies, the primary cell culture, genotyping and the animal facility management. Beyond that she organizes the laboratory and is in charge of the order management.
Her former work at the LMU Munich was focused on immunology, neuroproteomics, experimental neuropathology and leading the histology laboratory for patient care and dissection.
In Michael Quante`s team Julia is responsible for immunohistochemical and immunofluorescent studies, the primary cell culture, genotyping and the animal facility management. Beyond that she organizes the laboratory and is in charge of the order management.
Julia Horstman (Study Coordinator)
After graduation as a chemical Technician focused on biochemistry Julia gained her first work experience working for a pioneering clinical stage biopharmaceutical company for cell-based and gene therapy products. During this time she begun to be interested in clinical studies and joined 2013 Quante group to establish and coordinate BarrettNet.
Alumni
Anna Brandtner (M. Sc.)
Marina Grether (MTLA)
Dr. rer. nat. Bettina Kunze (né Höhl)
Magdalena Liebl (M. Sc.)
Dr. med. Carlo Maurer
Dr. med. Moritz Middelhoff
Dr. rer. nat. Natasha Stephens Münch
Steffi Neupert
Dr. rer. nat. Andreas Nuber
Agnieszka Pastula, PhD
Dr. med. univ. Raphael Schellnegger
Dr. rer. nat. Marc Tänzer
Hsin-Yu Fang, PhD
Marina Grether (MTLA)
Dr. rer. nat. Bettina Kunze (né Höhl)
Magdalena Liebl (M. Sc.)
Dr. med. Carlo Maurer
Dr. med. Moritz Middelhoff
Dr. rer. nat. Natasha Stephens Münch
Steffi Neupert
Dr. rer. nat. Andreas Nuber
Agnieszka Pastula, PhD
Dr. med. univ. Raphael Schellnegger
Dr. rer. nat. Marc Tänzer
Hsin-Yu Fang, PhD
